Classic I Pod problem

I've discovered my ITunes icon has disappeared from the desktop, it's completely gone from my computer with all my 500+ tunes. What will happen if I sync my Ipod Classic & 500+ tunes to my new downloaded ITunes? will I lose them

via iLounge Forums http://forums.ilounge.com/ipod-classic-legacy-ipods/278285-classic-i-pod-problem.html